KMID : 0385219990090030041
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Korean Journal of Gerontology 1999 Volume.9 No. 3 p.41 ~ p.45
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Effects of Water Extract of Cibotii Rhizoma on Serum Sex Hormone Levels in Ovariectomized Rats
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Kim Mi-Rye
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Abstract
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The effect of water extract of Cibotii Rhizoma on the levels of serum sex hormones and uterine weight were investigated in ovariectomized(OVX) rats. Female Sprague-Dawley rats with a body weight of 240 g were undergone ovariectomy or sham operation. The ovariectomy caused significant decrease in serum levels of estrogen androstenedione, testosterone and in uterine weight compared to those of sham-operated animals. Administration of water extract of Cibotii Rhizoma significantly elevated ovariectomy-induced decrease in serum levels of estrogen, androstenedione, testosterone. These findings suggest the protective effect water extract of Cibotii Rhizoma against bone low in postmenopausal osteoporosis.
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KEYWORD
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Water extract of Cibotii Rhizoma, Estrogen, Uterine weight, Ovariectomized(OVX) rats, Postmenopausal osteoporosis
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